HIV
This microscopic image in false color shows the HIV virus up close. Famous for its ability to evolve and evade drugs designed against it, HIV appears vulnerable to a new drug that speeds up the mutation process. It takes time and may not work for all patients, but early clinical trials are promising.
HIV is notorious for its ability to mutate and evade drugs designed to destroy it. Now scientists are testing a new drug that actually speeds up that rate of change in the hope that the deadly virus will mutate itself to death.
"The HIV virus is so dependent on mutation that it really lives on the edge of existence," said John Reno, Chief Operating Officer for Koronis Pharmaceuticals, the company developing a drug called KP-1461. "But we figured that if we could increase this mutation rate, [HIV] might finally fall off that edge."
KP-1461 is a mutagen, meaning it encourages mutation, and has been in development for several years by the scientists at Koronis Pharmaceuticals.